Offer Description

The mission of the Translational Synthetic Biology lab is to develop transformative technologies for human health. The Translational Synthetic Biology lab is part of  The Department of Experimental and Health Sciences – Faculty of Health and Life Sciences (DCEXS – FCSV) at Pompeu Fabra University (Barcelona) is specialized in Biomedical Research. Our lab is located at the PRBB in Barcelona one of the largest hubs of biomedical research of southern Europe.

The vast expansion of gene editing technologies and therapeutic enzymes holds big promise in treating many diseases. However, the challenge of how to efficiently deliver those tools to specific cell types and tissues remains to be solved. In our lab, we have developed a synthetic evolution platform that uses molecular biology and machine learning frameworks to drive evolution of delivery vehicles with the potential to target any desired cell type with unprecedented precision.

We are seeking a passionate, impact-motivated scientist and problem solver who wishes to participate in a fast-paced, dynamic research environment. The developed work will involve performing screens in T cells and other primary cell types, with the aim to evaluate fitness effects of various engineered proteins and model diseases phenotypes.

The project will involve Interactions with industry and Key opinion leaders in the field, in a vibrant ecosystem translation projects and spin-off companies.

Expected starting date: February of 2023.

Requirements

Research Field
Biological sciences » Biological engineering
Education Level
Master Degree or equivalent
Skills/Qualifications

MSc or PhD in biology, biotechnology, genetics, experimental or health sciences; or equivalent relevant experience.

Specific Requirements
  • Confidence in primary cell culture and measurement of cellular behaviors.
  • Curiosity and motivation to applied novel biotechnological solutions.
  • Excellent team player who enjoys working in a fast-evolving research environment.
  • Previous experience with T-cells and PBMCs manipulation.
  • Interest in applied genetic engineering and synthetic biology.
  • Previous experience in CRISPR or other pooled screens will be valued.
  • Previous experience in next generation sequencing and single cell technologies be valued
Languages
ENGLISH
Level
Excellent
Research Field
Biological sciences » Biological engineeringTechnology » Biotechnology
Years of Research Experience
1 – 4

Additional Information

Benefits

The candidate will receive a full-time contract and an annual salary according to the UPF salary guidelines. She/he will be able to receive training in complementary through courses of Pompeu Fabra University and the PRBB Intervals Program.
The candidate will participate in a highly translational project with Interactions with industry and spin-off environment.

Selection process

Please send the following documents:
– CV
– Cover letter
To the email address dimitrie.ivancic@upf.edu with “T-CELL ENGINEER” and your name in the email title.
Confidentiality in document handling and equality of opportunities policy are guaranteed by Pompeu Fabra University.

More info here

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